Chronic electronic cigarette exposure in mice induces features of COPD in a nicotine dependent manner Thorax Smoking cigarettes has long been proven to cause severe lung damage, including chronic obstructive pulmonary disease (COPD), emphysema, and lung cancer. Over time, cigarette smoke destroys lung tissue, fills airways with tar, Resources Tobacco Free Living E Cigarettes and Vaping PPAC Central Frontiers Inhalation of nicotine containing electronic cigarette vapor exacerbates the features of COPD by inducing ferroptosis in ENaC overexpressing mice Chronic obstructive pulmonary disease develops over decades and we are missing the window to prevent it