Glucose 6 Phosphate Dehydrogenase Deficiency Activates Endothelial Cell and Leukocyte Adhesion Mediated via the TGF NADPH Oxidases ROS Signaling Pathway Glucose 6 phosphate dehydrogenase (G6PD) deficiency X linked recessive Xq28 is not true recessive as heterozygotes can express the trait; G6PD > No NADPH > No RBC glutathione protection > free radical damage hemolysis Glucose6phosphate dehydrogenase deficiency in transfusion medicine: the unknown risks Francis 2013 Vox Sanguinis Wiley Online Library Loss of glucose 6 phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells PNAS Treatment strategies for glucose 6 phosphate dehydrogenase deficiency: past and future perspectives: Trends in Pharmacological Sciences Know About G6PD Deficiency G6PD deficiency is one of the most common inherited metabolic disorders. When triggered, it can lead to haemolytic anaemia, which may cause symptoms such as paleness,