Pentose Phosphate Pathway: High Yield Biochemistry Notes Oncourse Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst Pentose Phosphate Cycle an overview ScienceDirect Topics The return of metabolism: biochemistry and physiology of the pentose phosphate pathway Stincone 2015 Biological Reviews Wiley Online Library Pentose Phosphate an overview ScienceDirect Topics The pentose phosphate pathway: An antioxidant defense and a crossroad in tumor cell fate ScienceDirect