Not feeling well? *Don't* reach for Tylenol! Here are 8 reasons why. Some experts maintain that if acetaminophen were a brand new drug up for approval today, it would *not* get approved at Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Dr. Tylenol (acetaminophen) is not something I use or give my children or recommend for pregnant women. It depletes glutathione, an extremely important antioxidant and detoxification agent in the human body. Glutathione or L Glutathione: What is Better for Skin? 5 Oxoprolinuria as a Cause for Metabolic Acidosis Renal Fellow Network Tylenol, Glutathione, Metals, and Folate Pathways: What Actually Helps Our Kids