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does ghk-cu cause receptor downregulation or tolerance ✨ How GHK Peptide Works 🚨 Signaling GHK acts as a “switch” for skin repair: Interacts with adenosine receptors → reduces inflammation Activates MAPK/ERK, PI3K/Akt, TGF-β pathways Stimulates fibroblasts & keratinocytes → boosts collagen, elastin