Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Citalopram Induced Oral Melanotic Macules in a Female Patient and a Review of the Literature Cureus Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Differentiating between early melanomas and melanocytic nevi: A state of the art review ScienceDirect A Case Report of Oral Malignant Melanoma: A Silent Killer Cureus Labial melanotic macule. B). Increased numbers of me lanocytes along Download Scientific Diagram