The peptide problem: Hype is outrunning the evidence 1209_S7_article_14 BPC 157: Science Backed Uses, Benefits, Dosage, and Safety Cholesterol Management: Introduction Life Extension Peptide Therapy in The Colony TX People talk about BPC 157 like it's one thing. It isn't. Oral BPC 157 stays local. It survives digestion long enough to act on the GI mucosa, then clears before it reaches systemic circulation.